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KMID : 1159320130150020165
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Korean Journal of Vision Science
2013 Volume.15 No. 2 p.165 ~ p.172
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Correlation analysis of artificial tear containing hydroxypropyl methylcellulose and hydrogel contact lens
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Cho Seon-Ahr
Sung A-Young
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Abstract
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Purpose: Artificial tear is considered as an important functional material to solve the irritation of contact lens wearers. Hydroxypropyl methylcellulose is one of the general materials used for artificial tear. In this study, the impacts of artificial tear including hydroxypropyl methylcellulose on the hydrogel contact lens were analyzed in various conditions. Methods: The cross-linking agent, EGDMA(ethylene glycol dimethacrylate) and HEMA (2-hydroxyethyl methacrylate) were determined to be used as the basic combination to produce a soft hydrogel contact lens. Also, NVP (n-vinyl-2-pyrrolidone) and MMA (methyl methacrylate) were added to this combination for classification of water content. The physical properties such as water content, refractive index, spectral transmittance and contact angle of produced contact lens were measured. Results: Measurement of the physical properties of the copolymerized polymer showed that water content, refractive index, visible ray transmittance and contact angle were in the range of 27.64~48.33%, 1.424~1.453, 82.0~92.0% and , respectively. In addition, for the measured physical property after soaking into artificial tear, the water content, refractive index and contact angle were in the range of 25.86~48.26%, 1.424~1.456, 76.0~92.0% and , respectively. The changes of the physical property depending on hydration time showed the increase of refractive index, decrease of water content, visible ray transmittance and contact angle. Conclusions: Artificial tear including hydroxypropyl methylcellulose which is used as wetting material, influenced water content, refractive index, contact angle and spectral transmittance of a hydrogel contact lenses.
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KEYWORD
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Artificial tear, refractive index, water content, contact angle
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